Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | C3AR1 | Q16581 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775855 | 0.96 | TBXAS1 (0.54) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8776050 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775935 | 0.84 | CYP3A4 (0.52) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775877 | 0.84 | CYP3A4 (0.52) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775881 | 0.82 | TBXAS1 (0.54) | ALDH1A1CYP2C9CYP2C19TBXAS1EPHX2 | |
| SCHEMBL8775822 | 0.81 | TBXAS1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19OPRM1 | |
| SCHEMBL8776082 | 0.80 | TBXAS1 (0.54) | ALDH1A1CYP2C9CYP2C19TBXAS1EPHX2 | |
| SCHEMBL8775931 | 0.80 | CYP3A4 (0.55) | ALDH1A1TSHRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8775820 | 0.78 | TBXAS1 (0.52) | ALDH1A1CYP2C9CYP2C19TBXAS1EPHX2 | |
| SCHEMBL8775928 | 0.78 | TBXAS1 (0.60) | CYP2C9CYP2C19TBXAS1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |