Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | CASR | P41180 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776039 | 0.87 | CASR (0.53) | TBXAS1EPHX2CASRALDH1A1SMN1; SMN2 | |
| SCHEMBL8775881 | 0.85 | TBXAS1 (0.54) | TBXAS1EPHX2CASRCYP2C9CYP2C19 | |
| SCHEMBL8776082 | 0.85 | TBXAS1 (0.54) | TBXAS1EPHX2CASRCYP2C9CYP2C19 | |
| SCHEMBL8775982 | 0.83 | CASR (0.51) | TBXAS1EPHX2CASRALDH1A1SMN1; SMN2 | |
| SCHEMBL8775820 | 0.83 | TBXAS1 (0.52) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8775928 | 0.83 | TBXAS1 (0.60) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8775837 | 0.82 | TBXAS1 (0.51) | TBXAS1EPHX2CASRCYP2C9CYP2C19 | |
| SCHEMBL8775932 | 0.81 | TBXAS1 (0.53) | TBXAS1EPHX2CASRCYP2C9CYP2C19 | |
| SCHEMBL8776013 | 0.81 | TBXAS1 (0.56) | TBXAS1EPHX2CASRCYP2C9CYP2C19 | |
| SCHEMBL8776121 | 0.81 | ALDH1A1 (0.51) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |