Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776110 | 0.96 | TBXAS1 (0.56) | TBXAS1EPHX2TBXA2RCYP2C9CYP2C19 | |
| SCHEMBL8776082 | 0.84 | TBXAS1 (0.54) | TBXAS1EPHX2TBXA2RCYP2C9CYP2C19 | |
| SCHEMBL8775881 | 0.84 | TBXAS1 (0.54) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8775822 | 0.83 | TBXAS1 (0.55) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8776013 | 0.81 | TBXAS1 (0.56) | TBXAS1EPHX2TBXA2RCYP2C9CYP2C19 | |
| SCHEMBL8776092 | 0.80 | TBXAS1 (0.58) | TBXAS1EPHX2TBXA2RCYP2C9CYP2C19 | |
| SCHEMBL8775928 | 0.80 | TBXAS1 (0.60) | TBXAS1EPHX2CYP2C9CYP2C19KCNA5 | |
| SCHEMBL8776121 | 0.78 | ALDH1A1 (0.51) | TBXAS1EPHX2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8775891 | 0.76 | TBXAS1 (0.62) | TBXAS1EPHX2TBXA2RCYP2C9CYP2C19 | |
| SCHEMBL8776039 | 0.76 | CASR (0.53) | TBXAS1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |