Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146094 | 0.98 | MMP8 (0.38) | MMP8CYP4F2CYP4A11PKMMEN1 | |
| SCHEMBL7517904 | 0.86 | MAPT (0.40) | MMP8CYP4F2CYP4A11PKMMEN1 | |
| SCHEMBL12504254 | 0.81 | CHRM1 (0.31) | — | |
| SCHEMBL20451216 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ATML3MBTL1LMNACA1 | |
| SCHEMBL22284808 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL574762 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL29037360 | 0.80 | CYP4F2 (0.38) | MMP8CYP4F2CYP4A11PKMMEN1 | |
| SCHEMBL408357 | 0.79 | LMNA (0.42) | MEN1KMT2AKDM4ELMNA | |
| SCHEMBL426668 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL29287145 | 0.78 | FAAH (0.47) | MEN1KMT2AMAPTATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578541-B1 | Process for the preparation of light alpha-olefines by oligomerisation of ethylene | INST FRANCAIS DU PETROLE (FR) | 1997-12-03 | — | — | EP | claimed |
| US-5496783-A | CATALYSIS WITH MIXTURE OF ZIRCONIUM COMPOUND, ACETAL OR KETAL, AND ORGANOALUMINUM BROMIDE OR CHLORIDE | INSTITUT FRANCAIS DU PETROLE (FR) | 1996-03-05 | — | — | US | claimed |
| US-5345023-A | Zirconium coordination catalysts with acetals and ketals | INSTITUT FRANCAIS DU PETROLE (FR) | 1994-09-06 | — | — | US | claimed |