Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26108377 | 0.82 | DRD2 (0.63) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL26492991 | 0.80 | HTR1A (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL26108581 | 0.80 | HTR1A (0.65) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8416329 | 0.76 | HTR1A (0.57) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9260064 | 0.76 | HTR1A (0.60) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL8776471 | 0.75 | HTR1A (0.56) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9633099 | 0.74 | HTR1A (0.75) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9024932 | 0.74 | HTR1A (0.58) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL7488440 | 0.74 | HTR1A (0.58) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9557902 | 0.74 | HTR1A (0.58) | DRD2HTR1AHTR2ADRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808166-A1 | MEDICAMENT INTENDED TO THE TREATMENT OF OBSESSIVE COMPULSIVE TROUBLES, SLEEP APNOEA, SEXUAL DYSFUNCTIONS, EMESA AND TRANSPORT SICKNESS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1997-11-26 | — | — | EP | claimed |
| WO-1997021439-A1 | MEDICAMENT INTENDED TO THE TREATMENT OF OBSESSIVE COMPULSIVE TROUBLES, SLEEP APNOEA, SEXUAL DYSFUNCTIONS, EMESA AND TRANSPORT SICKNESS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1997-06-19 | — | — | WO | claimed |