SCHEMBL8776586

SCHEMBL8776586

C=Cc1ccc(COCC2(CC)COC(=O)OC2)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17069791 0.87 TSHR (0.33)
SCHEMBL16019157 0.84
SCHEMBL8776631 0.78 PRKCA (0.38)
SCHEMBL13770597 0.78 TDP1 (0.35)
SCHEMBL14003898 0.75 PRKCA (0.31)
SCHEMBL641157 0.75 ALDH1A1 (0.30)
SCHEMBL36601 0.74 TSHR (0.38) MEN1KMT2A
SCHEMBL12200957 0.73 CHRNA7 (0.39)
SCHEMBL13721129 0.73 TSHR (0.37) MEN1KMT2A
SCHEMBL3161401 0.73 TSHR (0.37) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665260-B1 Curable resin composition NIPPON PAINT CO LTD (JP) 1997-12-29 EP claimed
EP-0687667-B1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO LTD (JP) 1997-12-03 EP claimed
EP-0687667-A1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO., LTD. (JP) 1995-12-20 EP claimed
US-5466754-A Cyclic alkylene carbonate groups, polyol, acid catalyst NIPPON PAINT CO., LTD. (JP) 1995-11-14 US claimed
EP-0665260-A2 Curable resin composition Nippon Paint Co., Ltd. (JP) 1995-08-02 EP claimed
EP-0665260-B1 Curable resin composition NIPPON PAINT CO LTD (JP) 1997-12-29 EP disclosed
EP-0687667-B1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO LTD (JP) 1997-12-03 EP disclosed
US-5534647-A Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO., LTD. (JP) 1996-07-09 US disclosed
EP-0687667-A1 Vinyl monomer having linear carbonate and hydroxyl groups NIPPON PAINT CO., LTD. (JP) 1995-12-20 EP disclosed
US-5466754-A Cyclic alkylene carbonate groups, polyol, acid catalyst NIPPON PAINT CO., LTD. (JP) 1995-11-14 US disclosed
EP-0665260-A2 Curable resin composition Nippon Paint Co., Ltd. (JP) 1995-08-02 EP disclosed