Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 12/20 | 0.45 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777306 | 0.92 | MEN1 (0.39) | MAP4K1MAOAMAOBL3MBTL1MEN1 | |
| SCHEMBL8777078 | 0.90 | MBNL1 (0.40) | MAP4K1HTR5A | |
| SCHEMBL8776528 | 0.87 | MEN1 (0.41) | MAP4K1MAOAMAOBL3MBTL1MEN1 | |
| SCHEMBL8775767 | 0.85 | MAP4K1 (0.47) | MAP4K1RPS6KA2L3MBTL1MEN1KMT2A | |
| SCHEMBL8776753 | 0.84 | MAOA (0.43) | MAP4K1MAOAMAOBL3MBTL1MEN1 | |
| SCHEMBL8777051 | 0.83 | NPC1 (0.37) | MAOAMAOBL3MBTL1 | |
| SCHEMBL8776831 | 0.82 | ALDH1A1 (0.49) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL8777316 | 0.82 | MBNL1 (0.40) | MAP4K1MAOAMAOBL3MBTL1MEN1 | |
| SCHEMBL29360950 | 0.81 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2A | |
| SCHEMBL3785974 | 0.81 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | MAP4K1 1097/4885RPS6KA2 3743/4885MAOA 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.