Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898941 | 1.00 | RAB9A (0.45) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL8776704 | 1.00 | RAB9A (0.45) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL7082815 | 0.86 | RAB9A (0.47) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL10480695 | 0.86 | RAB9A (0.47) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL8776709 | 0.85 | ALOX15 (0.49) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL8776680 | 0.85 | ALOX15 (0.49) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL9185477 | 0.84 | LDHA (0.47) | RAB9ANPSR1L3MBTL1CA1CA2 | |
| SCHEMBL31556283 | 0.82 | KMT2A (0.58) | NPSR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16119286 | 0.79 | AOC3 (0.47) | RAB9ANPSR1MEN1KMT2AAOC3 | |
| SCHEMBL16228151 | 0.79 | AOC3 (0.47) | RAB9ANPSR1MEN1KMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113789353-B | Preparation method of (2S, 3S) -2-chloro-3-hydroxy ester compound | 复旦大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-113789353-A | Preparation method of (2S,3S) -2-chloro-3-hydroxy ester compound | 复旦大学 | 2021-12-14 | — | — | CN | disclosed |
| EP-0808824-A2 | Process for preparing optically active 2-halogeno-3-hydroxypropionic acid ester | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |
| EP-0447938-B1 | Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds | TANABE SEIYAKU CO (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5204248-A | Enzymatic reduction of corresponding oxo derivative; intermediate for diltiazem | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5081240-A | PROCESS FOR THE PREPARATION OF BENZOTHIAZEPIN-ONE DERIVATIVES | SANOFI (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0447938-A1 | Process for preparing 2-halogeno-3-hydroxy-3-phenyl-propionic acid ester compounds | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |