Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | METAP2 | P50579 | 1/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.63 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 3/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226871 | 0.89 | APEX1 (0.64) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL10649706 | 0.87 | ALDH1A1 (0.62) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL20022705 | 0.87 | APEX1 (0.57) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL20022683 | 0.87 | HPGD (0.68) | KMT2AHPGDLMNAAPEX1TP53 | |
| SCHEMBL11901003 | 0.87 | KMT2A (0.89) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL31680569 | 0.87 | KMT2A (0.89) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL12062479 | 0.82 | CA2 (0.76) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8635709 | 0.81 | KMT2A (1.00) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL1984940 | 0.81 | KMT2A (1.00) | KMT2AHPGDGAALMNAL3MBTL1 | |
| SCHEMBL9163561 | 0.81 | KMT2A (0.54) | KMT2AHPGDGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809708-A1 | POTENTIATORS OF ANTIBACTERIAL AGENTS | Microcide Pharmaceuticals, Inc. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996024684-A1 | POTENTIATORS OF ANTIBACTERIAL AGENTS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1996-08-15 | — | — | WO | disclosed |