Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878149 | 0.78 | POLB (0.44) | POLBTSHRALDH1A1KDM4ERECQL | |
| SCHEMBL1076574 | 0.77 | TSHR (0.50) | HDAC1TSHRALDH1A1KDM4EHTT | |
| SCHEMBL504013 | 0.77 | ALDH1A1 (0.57) | HDAC1TSHRALDH1A1HTTLMNA | |
| SCHEMBL8905858 | 0.76 | ALDH1A1 (0.49) | HDAC1TSHRALDH1A1HTTLMNA | |
| SCHEMBL11042477 | 0.76 | ALDH1A1 (0.49) | HDAC1TSHRALDH1A1HTTLMNA | |
| Hydrogen Sulfide SCHEMBL27877649 | 0.75 | ALDH1A1 (0.55) | HDAC1TSHRALDH1A1HTTLMNA | |
| Hydrogen Sulfide SCHEMBL28874622 | 0.75 | ALDH1A1 (0.55) | HDAC1TSHRALDH1A1HTTLMNA | |
| SCHEMBL8784250 | 0.74 | ALDH1A1 (0.47) | HDAC1TSHRALDH1A1HTTLMNA | |
| SCHEMBL8904807 | 0.74 | TSHR (0.47) | HDAC1TSHRALDH1A1CYP2C19MAPK1 | |
| SCHEMBL27506956 | 0.74 | ALDH1A1 (0.47) | HDAC1TSHRALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |