Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27877649 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| Hydrogen Sulfide SCHEMBL28874622 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL6761465 | 0.90 | ALDH1A1 (0.52) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL3470651 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL22341302 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL6758063 | 0.88 | CYP2C19 (0.55) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL22341336 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL1076574 | 0.88 | TSHR (0.50) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| SCHEMBL11042477 | 0.86 | ALDH1A1 (0.49) | ALDH1A1TSHRHDAC1CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL21632037 | 0.86 | ALDH1A1 (0.49) | ALDH1A1TSHRHDAC1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117776900-A | Preparation method of 2-phenyl-2-ethylbutyric acid | 安庆双启医药科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-20130281729-A1 | CONTINUOUS METHOD FOR THE CARBONYLATION OF ALCOHOLS, IN PARTICULAR OF PHENYL ALCOHOLS | AET GROUP (FR) | 2013-10-24 | — | — | US | claimed |
| EP-2651870-A2 | CONTINUOUS METHOD FOR THE CARBONYLATION OF ALCOHOLS, IN PARTICULAR OF PHENYL ALCOHOLS | Aet Group (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080647-A2 | CONTINUOUS METHOD FOR THE CARBONYLATION OF ALCOHOLS, IN PARTICULAR OF PHENYL ALCOHOLS | AET GROUP (FR) | 2012-06-21 | — | — | WO | claimed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | claimed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| EP-1284957-B1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2008-05-07 | — | — | EP | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | PLIANT THERAPEUTICS INC (US) | 2024-08-15 | — | — | US | disclosed |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| CN-117776900-A | Preparation method of 2-phenyl-2-ethylbutyric acid | 安庆双启医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117776900-A | Preparation method of 2-phenyl-2-ethylbutyric acid | 安庆双启医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-0258089-A1 | Process for preparing solid components of catalysts, or precursors of such components, in the form of microspheroidal particles, suitable for the preparation of ethylene polymers | Montedison S.p.A. (IT) | 1988-03-02 | — | — | EP | disclosed |
| EP-0255790-A1 | Process for the polymerization of alpha-olefins or of their mixtures with minor amounts of ethylene, by means of catalysts comprising solid components or precursors of such components, in the form of microspheroidal particles | Montedison S.p.A. (IT) | 1988-02-10 | — | — | EP | disclosed |
| US-4146637-A | ANTIALLERGENS | LUDWIG MERCKLE K.G., CHEM. PHARM. FABRIK (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4117144-A | ANTIDEPRESSANTS | AB KABI (SE) | 1978-09-26 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | ALDH1A1 2168/4885TSHR 2567/4885HDAC1 571/4885 |
| US-20130281729-A1 | CONTINUOUS METHOD FOR THE CARBONYLATION OF ALCOHOLS, IN PARTICULAR OF PHENYL ALCOHOLS | ADH1A, ADH5, ADH1C | ALDH1A1 26/4885TSHR 3689/4885HDAC1 1741/4885 |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | ITGB6, ITGA1, ITGB1 | ALDH1A1 2168/4885TSHR 2567/4885HDAC1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.