Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750487 | 1.00 | HSD11B1 (0.44) | HSD11B1CA1CA2ATML3MBTL1 | |
| SCHEMBL9692259 | 0.85 | ATM (0.50) | HSD11B1CA1CA2ATML3MBTL1 | |
| SCHEMBL9750499 | 0.84 | HCAR2 (0.50) | CES2CES1KMT2ANPC1MAPT | |
| SCHEMBL16108980 | 0.83 | GAA (0.43) | HSD11B1CA1CA2ATML3MBTL1 | |
| SCHEMBL2234611 | 0.80 | CRHBP (0.44) | HSD11B1KMT2AMAPTMAPK1CHRNB2 | |
| SCHEMBL18316474 | 0.80 | CRHBP (0.44) | HSD11B1KMT2AMAPTMAPK1CHRNB2 | |
| SCHEMBL31354802 | 0.80 | CRHBP (0.44) | HSD11B1KMT2AMAPTMAPK1CHRNB2 | |
| SCHEMBL16109494 | 0.80 | ATM (0.40) | HSD11B1CA1CA2ATML3MBTL1 | |
| SCHEMBL16109050 | 0.80 | ALDH1A1 (0.46) | ATML3MBTL1KMT2ANPC1MAPT | |
| SCHEMBL16108652 | 0.80 | HPGD (0.43) | HSD11B1CA1CA2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453330-B2 | Process for the preparation of (-) (2R,3S)-2,3-epoxy-3-(4-methoxyphenyl) propionic acid methylester and its enantiomer | SYNTHELABO (FR) | 1997-12-03 | — | — | EP | claimed |
| JP-2145564-A | — | — | None | — | — | JP | disclosed |
| JP-4217969-A | — | — | None | — | — | JP | disclosed |
| US-RE34935-E | Method for preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one and chlorinated derivatives thereof | SYNTHELABO (FR) | 1995-05-09 | — | — | US | disclosed |
| JP-H04217969-A | PREPARATION OF (-)-(METHYL-(2R,3S)-2,3-EPOXY-3-(4-METHOXYPHENYL)PROPIONATE) AND ENANTIOMER THEREOF | SYNTHELABO SA | 1992-08-07 | — | — | JP | disclosed |
| JP-H02145564-A | PREPARATION OF PROPIONIC ACID DERIVATIVE | SYNTHELABO SA | 1990-06-05 | — | — | JP | disclosed |