Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115959 | 0.87 | HCAR2 (0.46) | HCAR2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL9750487 | 0.84 | HSD11B1 (0.44) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL8776897 | 0.84 | HSD11B1 (0.44) | CHRNA1CHRNGCHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2234611 | 0.82 | CRHBP (0.44) | HCAR2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL31354802 | 0.82 | CRHBP (0.44) | HCAR2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL18316474 | 0.82 | CRHBP (0.44) | HCAR2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL11833782 | 0.79 | CRHBP (0.41) | MEN1KMT2AADAM17LMNAHCRTR2 | |
| SCHEMBL9691742 | 0.78 | ADAM17 (0.48) | HCAR2ADAM17LMNAMAPTTDP1 | |
| SCHEMBL7448247 | 0.75 | HSD11B1 (0.45) | MEN1KMT2AALDH1A1MAPTGRIN2B | |
| SCHEMBL8115242 | 0.73 | HTT (0.53) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4217969-A | — | — | None | — | — | JP | disclosed |
| JP-H04217969-A | PREPARATION OF (-)-(METHYL-(2R,3S)-2,3-EPOXY-3-(4-METHOXYPHENYL)PROPIONATE) AND ENANTIOMER THEREOF | SYNTHELABO SA | 1992-08-07 | — | — | JP | disclosed |