SCHEMBL8777576

SCHEMBL8777576

CCOc1cc(N(CC)CC)ccc1C(OC(c1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1)c1ccc(N(CC)CC)cc1OCC)c1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 16/20 0.45
TSHR P16473 1/20 0.44
CNR1 P21554 4/20 0.41
CYP2C19 P33261 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777665 0.89 ALDH1A1 (0.39) CNR2TSHR
SCHEMBL8777563 0.85 NOX1 (0.40) CNR2TSHRCNR1
SCHEMBL8777629 0.83 ALDH1A1 (0.37) TSHR
SCHEMBL8777652 0.81 CNR2 (0.44) CNR2TSHRCNR1CYP2C19NR1H2
SCHEMBL8777827 0.80 ALDH1A1 (0.41) CNR2TSHR
SCHEMBL8777670 0.80 MAPK1 (0.38) CNR2
SCHEMBL8777597 0.79 BACE1 (0.42) CNR2TSHR
SCHEMBL8777543 0.79 ALDH1A1 (0.34) TSHR
SCHEMBL8777634 0.78 CNR2 (0.41) CNR2CNR1NR1H2NR1H3
SCHEMBL8777676 0.77 ALDH1A1 (0.35) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed