Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777563 | 0.93 | NOX1 (0.40) | BACE1RXRANOX1CNR2HTR1A | |
| SCHEMBL8777670 | 0.90 | MAPK1 (0.38) | BACE1RXRANOX1CNR2MEN1 | |
| SCHEMBL8777634 | 0.86 | CNR2 (0.41) | BACE1RXRANOX1CNR2NPY1R | |
| SCHEMBL8777561 | 0.84 | S100B (0.43) | BACE1NOX1CNR2MAPTNPSR1 | |
| SCHEMBL8777642 | 0.80 | TDP1 (0.41) | BACE1CNR2MEN1KMT2AMAPT | |
| SCHEMBL8777576 | 0.79 | CNR2 (0.45) | CNR2TSHR | |
| SCHEMBL8777700 | 0.79 | MEN1 (0.35) | CNR2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8777736 | 0.79 | APP (0.41) | NOX1LMNAMEN1KMT2AMAPT | |
| SCHEMBL8777596 | 0.79 | ALDH1A1 (0.45) | BACE1RXRALMNAMEN1KMT2A | |
| SCHEMBL8777724 | 0.78 | CALM1 (0.34) | RXRAMEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587184-B1 | Pressure sensitive recording materials | NEW OJI PAPER CO LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5478793-A | Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0587184-A2 | Pressure sensitive recording materials | NEW OJI PAPER CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |