SCHEMBL8777634

SCHEMBL8777634

CCCCN(CCCC)c1ccc(C(OCc2ccccc2)c2ccc(N(CC)CC)cc2OCC)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.41
RXRA P19793 3/20 0.37
HNF4A P41235 1/20 0.37
NR1H2 P55055 2/20 0.36
NR1H3 Q13133 2/20 0.36
NOX1 Q9Y5S8 1/20 0.36
BACE1 P56817 1/20 0.36
KCNH2 Q12809 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
CNR1 P21554 1/20 0.33
SLC16A3 O15427 1/20 0.32
SLC16A1 P53985 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777563 0.93 NOX1 (0.40) CNR2RXRAHNF4ANOX1BACE1
SCHEMBL8777670 0.87 MAPK1 (0.38) CNR2RXRANOX1BACE1ALDH1A1
SCHEMBL8777597 0.86 BACE1 (0.42) CNR2RXRANOX1BACE1KDM4E
SCHEMBL8777547 0.84 SLC16A3 (0.36) CNR2RXRAHNF4AALDH1A1SLC16A3
SCHEMBL8777671 0.79 RXRA (0.37) CNR2RXRAHNF4AGAASLC16A3
SCHEMBL8777724 0.79 CALM1 (0.34) RXRAHNF4AALDH1A1GAA
SCHEMBL8777642 0.79 TDP1 (0.41) CNR2BACE1ALDH1A1POLBCNR1
SCHEMBL8777576 0.78 CNR2 (0.45) CNR2NR1H2NR1H3CNR1
SCHEMBL8777544 0.78 CNR2 (0.36) CNR2RXRAKDM4EALDH1A1POLB
SCHEMBL8777736 0.78 APP (0.41) NOX1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed