SCHEMBL8777563

SCHEMBL8777563

CCOc1cc(N(CC)CC)ccc1C(OCc1ccccc1)c1ccc(N(CC)CC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 0.40
CNR2 P34972 9/20 0.40
BACE1 P56817 1/20 0.39
RXRA P19793 2/20 0.39
CNR1 P21554 2/20 0.37
TSHR P16473 1/20 0.36
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
HTR1A P08908 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
HNF4A P41235 1/20 0.35
AOC3 Q16853 1/20 0.34
SLC6A9 P48067 1/20 0.34
SLC6A5 Q9Y345 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777670 0.94 MAPK1 (0.38) NOX1CNR2BACE1RXRAAOC3
SCHEMBL8777597 0.93 BACE1 (0.42) NOX1CNR2BACE1RXRATSHR
SCHEMBL8777634 0.93 CNR2 (0.41) NOX1CNR2BACE1RXRACNR1
SCHEMBL8777642 0.85 TDP1 (0.41) CNR2BACE1CNR1AOC3MEN1
SCHEMBL8777576 0.85 CNR2 (0.45) CNR2CNR1TSHR
SCHEMBL8777736 0.84 APP (0.41) NOX1MEN1LMNAMAPTRAB9A
SCHEMBL8777700 0.84 MEN1 (0.35) CNR2CNR1TSHRMEN1KMT2A
SCHEMBL8777741 0.83 SLC2A1 (0.42) AOC3MEN1KMT2A
SCHEMBL8777724 0.83 CALM1 (0.34) RXRATSHRHNF4AMEN1KMT2A
SCHEMBL8777625 0.83 CCR5 (0.38) CNR2CNR1TSHRNPY2RADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed