SCHEMBL8777596

SCHEMBL8777596

CCOc1cc(N(CC)CC)ccc1C(OC)c1ccc(N(CC)CC)cc1OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
L3MBTL1 Q9Y468 5/20 0.45
TERT O14746 1/20 0.39
MAPT P10636 6/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
RAB9A P51151 3/20 0.38
LMNA P02545 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RXRA P19793 3/20 0.38
RXRB P28702 2/20 0.38
RXRG P48443 2/20 0.38
S100B P04271 1/20 0.38
HTT P42858 2/20 0.36
NPC1 O15118 2/20 0.35
GAA P10253 1/20 0.35
GRK6 P43250 1/20 0.35
HIF1A Q16665 1/20 0.35
GFER P55789 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777827 0.91 ALDH1A1 (0.41) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL8777842 0.87 ALDH1A1 (0.39) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL13748743 0.83 RXRA (0.48) ALDH1A1L3MBTL1TERTSMN1; SMN2RXRA
SCHEMBL8777665 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL8777547 0.83 SLC16A3 (0.36) ALDH1A1L3MBTL1MAPTMEN1KMT2A
SCHEMBL8777612 0.80 S100B (0.51) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL8777629 0.80 ALDH1A1 (0.37) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL5010120 0.79 GRK6 (0.41) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL8777590 0.79 ALDH1A1 (0.41) ALDH1A1L3MBTL1TERTMAPTMEN1
SCHEMBL8777597 0.79 BACE1 (0.42) ALDH1A1L3MBTL1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed