Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18390581 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL23556463 | 0.79 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL27072953 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1005825 | 0.74 | HSD11B1 (0.31) | — | |
| SCHEMBL9328718 | 0.70 | CHRM2 (0.50) | — | |
| SCHEMBL24637968 | 0.67 | SLC6A3 (0.39) | NPSR1 | |
| SCHEMBL24638030 | 0.65 | OPRM1 (0.41) | NPSR1 | |
| SCHEMBL2885603 | 0.64 | ALDH1A1 (0.53) | ALDH1A1POLBNPSR1 | |
| SCHEMBL2886732 | 0.64 | — | — | |
| SCHEMBL25469108 | 0.64 | GBA1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |