Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8946231 | 0.99 | F10 (0.42) | F10MAPTLPAR1CYP1A1CYP1A2 | |
| SCHEMBL8777858 | 0.84 | F10 (0.49) | F10MAPTLPAR1CYP1A1CYP1A2 | |
| SCHEMBL8778019 | 0.77 | MAOB (0.67) | MEN1KMT2A | |
| SCHEMBL8777901 | 0.76 | EPHX2 (0.52) | F10MAPTLPAR1MEN1KMT2A | |
| SCHEMBL8804145 | 0.74 | MAOA (0.40) | — | |
| SCHEMBL8778117 | 0.71 | F10 (0.47) | F10MAPTLPAR1CYP1A1CYP1A2 | |
| SCHEMBL8777906 | 0.71 | F10 (0.47) | F10MAPTLPAR1CYP1A1CYP1A2 | |
| SCHEMBL10537786 | 0.71 | MAPT (0.67) | MAPTHTR3AHTR4MEN1KMT2A | |
| SCHEMBL8778033 | 0.71 | HDAC1 (0.50) | F10MAPTLPAR1CYP1A1CYP1A2 | |
| SCHEMBL10539974 | 0.70 | MAPT (0.56) | MAPTHTR3AHTR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |