SCHEMBL8777945

SCHEMBL8777945

CN(C)[SiH2]CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
AOC3 Q16853 3/20 0.48
SIGMAR1 Q99720 6/20 0.45
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272425 0.87 SIGMAR1 (0.52) TAAR1AOC3SIGMAR1
SCHEMBL2154293 0.76 TSHR (0.48) TAAR1AOC3SIGMAR1ALDH1A1TSHR
SCHEMBL8384814 0.73 ALDH1A1 (0.48) TAAR1AOC3ALDH1A1HPGDALOX15
SCHEMBL8382309 0.72 ALDH1A1 (0.52) TAAR1SIGMAR1ALDH1A1HPGDALOX15
Hydrochloric Acid SCHEMBL4465542 0.71 ALDH1A1 (0.46) TAAR1AOC3ALDH1A1HPGDALOX15
Hydrochloric Acid SCHEMBL4465538 0.71 ALDH1A1 (0.46) TAAR1AOC3ALDH1A1HPGDALOX15
SCHEMBL11526046 0.71 ALDH1A1 (0.65) TAAR1SIGMAR1ALDH1A1HPGDALOX15
Hydrochloric Acid SCHEMBL1030795 0.70 ALDH1A1 (0.50) TAAR1ALDH1A1HPGDALOX15ALOX12
Chloromethane SCHEMBL29048090 0.70 ALDH1A1 (0.44) TAAR1AOC3ALDH1A1HPGDALOX15
SCHEMBL8575149 0.70 TP53 (0.46) TAAR1AOC3SIGMAR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671483-B1 Method for vapor deposition of a ceramic coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM SPA (IT) 1997-12-29 EP claimed
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP claimed
EP-0671483-A1 Ceramic vapor deposited coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM S.p.A. (IT) 1995-09-13 EP claimed
US-5424095-A Decomposing organosilicon precursor inside chemical reactor to form film of ceramic material on surface; prevents coking ENIRICERCHE S.P.A. (IT) 1995-06-13 US claimed
EP-0540084-A1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM S.p.A. (IT) 1993-05-05 EP claimed
US-5208069-A Silane precursor ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-05-04 US claimed
CN-1477949-A Cosmetic care or make-up composition for keratin materials comprising aliphatic ester and oil whose mole mass is 650 to 10000g/mol �ź㴫 2004-02-25 CN disclosed
EP-0671483-B1 Method for vapor deposition of a ceramic coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM SPA (IT) 1997-12-29 EP disclosed
EP-0540084-B1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM SPA (IT) 1996-09-04 EP disclosed
EP-0671483-A1 Ceramic vapor deposited coating using a steam-containing carrier gas and non-alkoxy silane precursors ENICHEM S.p.A. (IT) 1995-09-13 EP disclosed
US-5424095-A Decomposing organosilicon precursor inside chemical reactor to form film of ceramic material on surface; prevents coking ENIRICERCHE S.P.A. (IT) 1995-06-13 US disclosed
EP-0540084-A1 Method for passivating the inner surface of a reactor subject to coking, by deposition of a ceramic coating, and method of pyrolyzing hydrocarbons ENICHEM S.p.A. (IT) 1993-05-05 EP disclosed
US-5208069-A Silane precursor ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1993-05-04 US disclosed