SCHEMBL8778030

SCHEMBL8778030

O=C(Oc1c(C(=O)O)cccc1-c1cccc2ccccc12)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
MCL1 Q07820 2/20 0.45
ACMSD Q8TDX5 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
GFER P55789 1/20 0.42
CDC25B P30305 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
SENP1 Q9P0U3 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
DEGS1 O15121 1/20 0.41
LDHA P00338 1/20 0.40
FABP3 P05413 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778066 0.84 HNF4A (0.51) ESR1ESR2CDC25BSENP1ALDH1A1
SCHEMBL7761009 0.82 GAA (0.48) NR4A1NR4A2NR4A3MCL1ACMSD
SCHEMBL8778012 0.81 SLC6A2 (0.49) MCL1ACMSDESR1ESR2KMT2A
SCHEMBL28724636 0.79 DEGS1 (0.44) NR4A1NR4A2NR4A3MCL1ACMSD
SCHEMBL7896440 0.76 KMT2A (0.58) ESR1ESR2KMT2AMEN1ALDH1A1
SCHEMBL8766835 0.75 ALDH1A1 (0.62) ESR1ESR2KMT2AMEN1SENP1
SCHEMBL6264269 0.75 HNF4A (0.53) ESR1ESR2CDC25BKMT2AMEN1
SCHEMBL27841250 0.74 NR4A1 (0.53) NR4A1NR4A2NR4A3MCL1ACMSD
SCHEMBL1641502 0.74 NR4A1 (0.70) NR4A1NR4A2NR4A3MCL1ACMSD
SCHEMBL7541679 0.73 KMT2A (0.59) ESR1ESR2KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed