SCHEMBL8766835

SCHEMBL8766835

Cc1cccc(C(=O)O)c1OC(=O)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
KDM4E B2RXH2 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
SENP1 Q9P0U3 1/20 0.47
ESR1 P03372 3/20 0.47
ESR2 Q92731 3/20 0.47
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
CA14 Q9ULX7 3/20 0.44
KMT2A Q03164 3/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11618541 0.89 KDM4E (0.68) ALDH1A1KDM4EHPGDHSD17B10ESR1
Hydrochloric Acid SCHEMBL30492909 0.85 KDM4E (0.59) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL8767097 0.82 SENP1 (0.45) ALDH1A1KDM4EHPGDHSD17B10SENP1
SCHEMBL8768064 0.81 SENP1 (0.44) ALDH1A1KDM4EHPGDHSD17B10SENP1
SCHEMBL8768312 0.81 SENP1 (0.44) ALDH1A1KDM4EHPGDHSD17B10SENP1
SCHEMBL28689049 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10CA1
SCHEMBL16297124 0.80 SENP1 (0.49) ALDH1A1KDM4ESENP1ESR1ESR2
SCHEMBL12884756 0.80 HPGD (0.64) ALDH1A1KDM4EHPGDHSD17B10ESR1
SCHEMBL28689047 0.80 L3MBTL1 (0.50) ALDH1A1KDM4EHPGDHSD17B10SENP1
SCHEMBL8778066 0.79 HNF4A (0.51) ALDH1A1HSD17B10SENP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585127-B1 Thermal Recording sheet JUJO PAPER CO LTD (JP) 1997-12-29 EP disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
US-5405821-A Containing a 4-hydroxyphenylarylsulfone color developer NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-04-11 US disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed