SCHEMBL391014

SCHEMBL391014

CCN(CC)c1ccc(C2c3ccc(N(C)C)cc3Oc3cc(N(C)C)ccc32)c(O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.44
ALDH1A1 P00352 12/20 0.44
MEN1 O00255 7/20 0.44
KMT2A Q03164 7/20 0.44
NPSR1 Q6W5P4 6/20 0.44
GAA P10253 6/20 0.44
NPC1 O15118 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
RAB9A P51151 2/20 0.44
GRK6 P43250 1/20 0.44
HIF1A Q16665 1/20 0.44
HTT P42858 6/20 0.43
TDP1 Q9NUW8 4/20 0.43
THRB P10828 1/20 0.43
SMN1; SMN2 Q16637 6/20 0.41
CASP1 P29466 3/20 0.41
CASP7 P55210 3/20 0.41
USP2 O75604 2/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020930 1.00 MAPT (0.44) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL390797 0.83 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL8778047 0.82 NPSR1 (0.46) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL11520111 0.77 MEN1 (0.48) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL4070707 0.75 NPC1 (0.45) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL18179775 0.75 MEN1 (0.43) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL3896114 0.75 MEN1 (0.43) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL82135 0.74 MEN1 (0.52) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL21396497 0.74 CYP3A4 (0.42) MAPTALDH1A1MEN1KMT2ANPSR1
SCHEMBL3907415 0.74 MEN1 (0.44) MAPTALDH1A1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 US disclosed
US-8101655-B2 Fluorescent dyes and complexes SMITH GERALD ARTHUR (GB) 2012-01-24 US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 US disclosed
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-10-07 US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 US disclosed
US-7674918-B2 Fluorescent dyes and complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2010-03-09 US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 US disclosed
US-20070238884-A1 Fluorescent Dyes and Complexes CAMBRIDGE ENTERPRISE LIMITED (GB) 2007-10-11 US disclosed
EP-1740947-A2 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2007-01-10 EP disclosed
WO-2005098437-A2 FLUORESCENT DYES AND COMPLEXES CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD (GB) 2005-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238884-A1 Fluorescent Dyes and Complexes F12, PYM1, ANXA6 MAPT 3961/4885ALDH1A1 1039/4885MEN1 3023/4885
US-20100256399-A1 FLUORESCENT DYES AND COMPLEXES F12, ANXA6, PYM1 MAPT 3957/4885ALDH1A1 1468/4885MEN1 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.