Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779056 | 0.79 | F7 (0.39) | KDM1A | |
| SCHEMBL8779058 | 0.79 | METAP1 (0.40) | KDM1A | |
| SCHEMBL8779030 | 0.79 | SIGMAR1 (0.39) | KDM1A | |
| SCHEMBL8779104 | 0.72 | ADRA2A (0.35) | — | |
| SCHEMBL8779005 | 0.72 | MAPT (0.33) | — | |
| SCHEMBL8779123 | 0.72 | TDP2 (0.36) | — | |
| SCHEMBL8778992 | 0.72 | TDP1 (0.39) | KDM1A | |
| SCHEMBL8778991 | 0.70 | SIGMAR1 (0.44) | — | |
| SCHEMBL8778942 | 0.69 | METAP1 (0.44) | KDM1A | |
| SCHEMBL8779060 | 0.69 | KDM1A (0.37) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606661-B1 | Octahydrophenanthrene derivatives and their use as NMDA-Antagonists | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| EP-0606661-A1 | Octahydrophenanthrene derivatives and their use as NMDA-Antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1994-07-20 | — | — | EP | disclosed |