Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779183 | 1.00 | REN (0.35) | RENCARM1PRMT6LNPEPACACB | |
| SCHEMBL8779157 | 0.90 | XIAP (0.40) | CARM1PRMT6ACACB | |
| SCHEMBL8779135 | 0.90 | XIAP (0.40) | CARM1PRMT6ACACB | |
| SCHEMBL8779220 | 0.89 | AAK1 (0.40) | RENLNPEP | |
| SCHEMBL8779165 | 0.89 | XIAP (0.38) | RENCARM1PRMT6LNPEP | |
| SCHEMBL8779325 | 0.89 | IKBKB (0.37) | CARM1PRMT6ACACBIKBKB | |
| SCHEMBL8779136 | 0.89 | IKBKB (0.37) | CARM1PRMT6ACACBIKBKB | |
| SCHEMBL8779278 | 0.88 | HTT (0.39) | CARM1PRMT6ACACB | |
| SCHEMBL8779212 | 0.86 | HPGD (0.38) | CARM1PRMT6IKBKB | |
| SCHEMBL8779176 | 0.86 | HPGD (0.38) | CARM1PRMT6IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |