Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230923 | 0.86 | SMN1; SMN2 (0.36) | GAAEGLN1ALDH1A1MAPTHPGD | |
| SCHEMBL4070937 | 0.84 | FTO (0.57) | EGLN2FTOGAAEGLN1ALDH1A1 | |
| SCHEMBL8374641 | 0.80 | GAA (0.46) | EGLN2FTOGAAEGLN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8809536 | 0.79 | GAA (0.45) | EGLN2FTOGAAEGLN1ALDH1A1 | |
| SCHEMBL3785068 | 0.77 | TDP1 (0.38) | ALDH1A1MAPTBLMMAPK8TDP1 | |
| SCHEMBL8779339 | 0.74 | EGLN2 (0.45) | EGLN2FTOGAAEGLN1HPGD | |
| SCHEMBL8883374 | 0.74 | FTO (0.69) | EGLN2FTOGAAEGLN1MAPT | |
| SCHEMBL4081448 | 0.73 | RAB9A (0.40) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL7611607 | 0.70 | EGLN2 (0.39) | EGLN2FTOGAAALDH1A1HPGD | |
| SCHEMBL7610436 | 0.69 | EGLN2 (0.38) | EGLN2FTOGAAEGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |