Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779141 | 0.94 | AAK1 (0.33) | CARM1PRMT6AAK1MAPTGSK3B | |
| SCHEMBL8779232 | 0.91 | GSK3B (0.39) | CARM1PRMT6AAK1MAPTGSK3B | |
| SCHEMBL8779221 | 0.88 | HTT (0.38) | CARM1PRMT6AAK1MAPTGSK3B | |
| SCHEMBL8779176 | 0.84 | HPGD (0.38) | CARM1PRMT6AAK1 | |
| SCHEMBL8779212 | 0.84 | HPGD (0.38) | CARM1PRMT6AAK1 | |
| SCHEMBL8779207 | 0.84 | CARM1 (0.31) | CARM1 | |
| SCHEMBL8779292 | 0.83 | CARM1 (0.35) | CARM1PRMT6AAK1CYP3A4 | |
| SCHEMBL8882279 | 0.83 | MAPT (0.35) | CARM1PRMT6AAK1MAPTGSK3B | |
| SCHEMBL8779316 | 0.82 | MME (0.39) | — | |
| SCHEMBL8779325 | 0.82 | IKBKB (0.37) | CARM1PRMT6MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |