Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895396 | 0.84 | GLA (0.36) | GLAHSD11B1L3MBTL1HTTITGB1 | |
| SCHEMBL1088117 | 0.71 | GLA (0.42) | GLAHSD11B1L3MBTL1KDM4EHTT | |
| SCHEMBL8779341 | 0.71 | ALDH1A1 (0.46) | HSD11B1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL6346843 | 0.71 | EPHX2 (0.43) | HSD11B1L3MBTL1MAPTGAAXBP1 | |
| SCHEMBL6378192 | 0.70 | MAPT (0.52) | GLAHSD11B1L3MBTL1KDM4EMAPT | |
| SCHEMBL10323133 | 0.70 | GLA (0.41) | GLAHSD11B1L3MBTL1KDM4EHTT | |
| SCHEMBL19557166 | 0.69 | HSD11B1 (0.48) | GLAHSD11B1L3MBTL1KDM4EHTT | |
| SCHEMBL3755487 | 0.69 | HSD11B1 (0.38) | GLAHSD11B1L3MBTL1KDM4EHTT | |
| SCHEMBL19557168 | 0.69 | HSD11B1 (0.48) | GLAHSD11B1L3MBTL1KDM4EHTT | |
| SCHEMBL12714 | 0.69 | HSD11B1 (0.48) | GLAHSD11B1L3MBTL1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |