Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779311 | 0.84 | RAB9A (0.50) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8779275 | 0.83 | NPC1 (0.62) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8779321 | 0.81 | NPC1 (0.54) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL3913163 | 0.79 | RAB9A (0.55) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL3909238 | 0.79 | L3MBTL1 (0.69) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8177453 | 0.76 | NPC1 (0.67) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8779332 | 0.76 | NPC1 (0.63) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8779333 | 0.76 | ALDH1A1 (0.60) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL3906094 | 0.76 | MAPK1 (0.62) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL3902870 | 0.75 | ALOX15 (0.59) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |
| EP-0579129-A2 | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1994-01-19 | — | — | EP | claimed |