Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.70 |
| ▸ | SRC | P12931 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376207 | 0.84 | MAPT (0.69) | ABL1SRCSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8779364 | 0.84 | SMN1; SMN2 (0.79) | ABL1SRCHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL8779340 | 0.83 | CYP1A2 (0.77) | ABL1SRCHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL3612969 | 0.82 | SMN1; SMN2 (0.76) | ABL1SRCHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9018863 | 0.82 | SMN1; SMN2 (0.72) | ABL1SRCHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL8779363 | 0.81 | HTT (0.73) | ABL1SRCHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL5173078 | 0.79 | MEN1 (0.70) | HTTSMN1; SMN2MEN1KMT2ACSNK2A2 | |
| SCHEMBL8779398 | 0.76 | ALDH1A1 (0.72) | ABL1SRCHTTSMN1; SMN2MEN1 | |
| SCHEMBL11337858 | 0.73 | KDM4E (0.66) | HTTSMN1; SMN2MEN1KMT2ACSNK2A2 | |
| SCHEMBL11337854 | 0.73 | KDM4E (0.66) | HTTSMN1; SMN2MEN1KMT2ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |
| EP-0579129-A2 | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1994-01-19 | — | — | EP | claimed |