Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779315 | 0.83 | SELL (0.48) | ALDH1A1HSD17B10SMN1; SMN2LMNAMEN1 | |
| P-Xylene SCHEMBL8779430 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1HSD17B10SMN1; SMN2LMNAMEN1 | |
| P-Cresol SCHEMBL8779429 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| Metacresol SCHEMBL8779348 | 0.79 | ACHE (0.53) | ALDH1A1ALOX15HSD17B10SMN1; SMN2LMNA | |
| Methane SCHEMBL5950714 | 0.74 | TRPA1 (0.94) | TRPA1ALDH1A1ALOX15HSD17B10LMNA | |
| SCHEMBL11332555 | 0.73 | MGAM (0.57) | TRPA1ALDH1A1ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL8779376 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12388 | 0.72 | — | — | |
| SCHEMBL1685227 | 0.72 | FBP1 (0.43) | ALDH1A1HSD17B10SMN1; SMN2LMNAHPGD | |
| SCHEMBL29406334 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |