Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TOP1 | P11387 | 2/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410176 | 0.90 | TSHR (0.62) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL11401919 | 0.90 | TNFSF11 (0.55) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL28742168 | 0.84 | ACHE (0.46) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL29210434 | 0.82 | KDM4E (0.44) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL18930726 | 0.78 | TSHR (0.56) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL8779405 | 0.77 | TOP1 (0.51) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL12094224 | 0.77 | TSHR (0.60) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL29440769 | 0.77 | KDM4E (0.67) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL1866980 | 0.77 | KDM4E (0.67) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL8350024 | 0.77 | TSHR (0.60) | TSHRKDM4EALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | claimed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |
| CN-102791803-B | Composition for ultraviolet absorbing member and ultraviolet absorbing member using same | SUMITOMO SEIKA CHEMICALS | 2015-07-01 | — | — | CN | disclosed |
| US-8540904-B2 | Composition for ultraviolet absorbent substance and ultraviolet absorbent substance comprising same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120313058-A1 | COMPOSITION FOR ULTRAVIOLET ABSORBENT SUBSTANCE AND ULTRAVIOLET ABSORBENT SUBSTANCE COMPRISING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
| CN-101125864-A | Heteroaromatic inhibitor for fructose-1,6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2008-02-20 | — | — | CN | disclosed |
| CN-100349904-C | Novel heteroaromatic inhibitors of fructose-1, 6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1900087-A | Novel heteroaromatic inhibitors of fructose 1,6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2007-01-24 | — | — | CN | disclosed |
| CN-1704423-A | Novel heteroaromatic inhibitors of fructose-1, 6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2005-12-07 | — | — | CN | disclosed |
| CN-1215076-C | Novel heteroaromatic inhibitors of fructose-1, 6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2005-08-17 | — | — | CN | disclosed |
| CN-1326459-A | Novel heteroaromatic inhibitors of fructose-1, 6-bisphosphatase | METABASIS THERAPEUTICS INC (US) | 2001-12-12 | — | — | CN | disclosed |
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4988687-A | Thiazoleoxyimineacetamido carboxymethylpyridinium derivatives of cephalosporins | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4280008-A | CHEMICAL INTERMEDIATES FOR OPTICALLY ACTIVE AMINO ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |