SCHEMBL8779408

SCHEMBL8779408

NCC(=O)NC(=O)Oc1nccc(OCC(F)(F)C(F)(F)C(F)(F)F)c1O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779207 0.93 CARM1 (0.31) CARM1
SCHEMBL8779238 0.89 CYP1A2 (0.36) CARM1
SCHEMBL9233029 0.85 KMT2A (0.41) CARM1
SCHEMBL8779141 0.84 AAK1 (0.33) CARM1
SCHEMBL8880853 0.82 CYP1A2 (0.31)
SCHEMBL8779326 0.80 SMN1; SMN2 (0.39) CARM1
SCHEMBL8779246 0.80 MAOB (0.43)
SCHEMBL8786282 0.80 CARM1 (0.33) CARM1
SCHEMBL8779273 0.78 IKBKB (0.38) CARM1
SCHEMBL8779270 0.78 CNR2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661269-B1 Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments HOECHST AG (DE) 1997-03-26 EP disclosed