Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779806 | 0.82 | MAPT (0.39) | KDM4EMAPTHPGDCYP1A2CYP3A4 | |
| SCHEMBL1941288 | 0.81 | EPAS1 (0.41) | MEN1KMT2AALDH1A1HSD17B10TDP1 | |
| SCHEMBL1939729 | 0.78 | VCAM1 (0.51) | MEN1KMT2AALDH1A1EPAS1TRPV4 | |
| SCHEMBL30540035 | 0.76 | TSHR (0.41) | KDM4EMAPTHPGDCYP3A4CYP2C19 | |
| SCHEMBL20870724 | 0.76 | XDH (0.40) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL25366711 | 0.76 | TSHR (0.41) | KDM4EMAPTHPGDCYP3A4CYP2C19 | |
| SCHEMBL320675 | 0.76 | GRM4 (0.38) | MEN1KMT2AALDH1A1HSD17B10TDP1 | |
| SCHEMBL29814208 | 0.76 | XDH (0.40) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL319459 | 0.76 | ACLY (0.47) | EPAS1TRPV4VEGFAACLY | |
| SCHEMBL31591563 | 0.76 | GRM4 (0.38) | MEN1KMT2AALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |