Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591563 | 1.00 | GRM4 (0.38) | GRM4ALDH1A1HSD17B10TDP1CA2 | |
| SCHEMBL1396710 | 0.85 | CA2 (0.36) | ALDH1A1HSD17B10TDP1CA2CA1 | |
| SCHEMBL1941288 | 0.82 | EPAS1 (0.41) | ALDH1A1HSD17B10TDP1EPAS1MEN1 | |
| SCHEMBL1939729 | 0.79 | VCAM1 (0.51) | GRM4ALDH1A1EPAS1MEN1KMT2A | |
| SCHEMBL15794073 | 0.79 | GAA (0.39) | GRM4ALDH1A1CHRM2CHRM1RRM1 | |
| SCHEMBL25366711 | 0.78 | TSHR (0.41) | ALDH1A1HSD17B10TDP1EPAS1MEN1 | |
| SCHEMBL20870724 | 0.78 | XDH (0.40) | ALDH1A1HSD17B10TDP1CA2CA1 | |
| SCHEMBL319459 | 0.78 | ACLY (0.47) | GRM4EPAS1SLC22A12TRPV4VEGFA | |
| SCHEMBL29814208 | 0.78 | XDH (0.40) | ALDH1A1HSD17B10TDP1CA2CA1 | |
| SCHEMBL30540035 | 0.78 | TSHR (0.41) | ALDH1A1HSD17B10TDP1EPAS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655405-B1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2023-06-07 | — | — | EP | disclosed |
| EP-3655405-B1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-115745910-A | Chemical compound | 安塔比奥公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-110446708-B | Chemical compound | 安塔比奥公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220315546-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2022-10-06 | — | — | US | disclosed |
| US-11299467-B2 | Chemical compounds | ANTABIO SAS (FR) | 2022-04-12 | — | — | US | disclosed |
| US-10889555-B2 | Sulfonamide compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-01-12 | — | — | US | disclosed |
| US-20200405697-A1 | Antitumor Agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-31 | — | — | US | disclosed |
| US-20200399235-A1 | Sulfonamide Compound or Salt Thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-24 | — | — | US | disclosed |
| US-20200339526-A1 | CHEMICAL COMPOUNDS | ANTABIO SAS (FR) | 2020-10-29 | — | — | US | disclosed |
| US-9096558-B2 | N-sulfonylbenzamide compounds | PFIZER LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| US-9096558-B2 | N-sulfonylbenzamide compounds | PFIZER LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| US-9096558-B2 | N-sulfonylbenzamide compounds | PFIZER LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| EP-2590957-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2014-11-12 | — | — | EP | disclosed |
| EP-2590957-B1 | N-SULFONYLBENZAMIDES AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | PFIZER LTD (GB) | 2014-11-12 | — | — | EP | disclosed |
| EP-2590957-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109696-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| US-20130109696-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| US-20130109696-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2013-05-02 | — | — | US | disclosed |
| WO-2012004714-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315546-A1 | CHEMICAL COMPOUNDS | MRPL21, MLX, TXN | GRM4 2788/4885ALDH1A1 1565/4885HSD17B10 3379/4885 |
| US-20200399235-A1 | Sulfonamide Compound or Salt Thereof | RNASEH1, SNRPA1, RRM2 | GRM4 4199/4885ALDH1A1 1103/4885HSD17B10 651/4885 |
| US-11299467-B2 | Chemical compounds | MRPL21, MLX, CFTR | GRM4 2945/4885ALDH1A1 1225/4885HSD17B10 3240/4885 |
| US-20130109696-A1 | Chemical Compounds | SCN1A, SCN7A, SCN1B | GRM4 2507/4885ALDH1A1 1451/4885HSD17B10 2972/4885 |
| US-10889555-B2 | Sulfonamide compound or salt thereof | RNASEH1, SNRPA1, RRM2 | GRM4 4199/4885ALDH1A1 1103/4885HSD17B10 651/4885 |
| US-20200339526-A1 | CHEMICAL COMPOUNDS | MRPL21, MLX, CFTR | GRM4 2945/4885ALDH1A1 1225/4885HSD17B10 3240/4885 |
| US-20200405697-A1 | Antitumor Agent | HNRNPR, RRM2, RRM2B | GRM4 3813/4885ALDH1A1 1397/4885HSD17B10 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.