Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780338 | 0.93 | SPHK1 (0.48) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL8780334 | 0.85 | LMNA (0.41) | LMNA | |
| SCHEMBL27881377 | 0.82 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL600713 | 0.82 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL30575899 | 0.82 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL1234977 | 0.82 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL7708644 | 0.82 | SPHK1 (0.52) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL8780304 | 0.81 | PLA2G1B (0.47) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL11026909 | 0.79 | SLC6A2 (0.34) | CYP2D6LMNAMAPTALDH1A1DNM1 | |
| SCHEMBL4446557 | 0.79 | SLC6A2 (0.34) | CYP2D6LMNAMAPTALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601668-B1 | Epoxy resin composition | SHELL INT RESEARCH (NL) | 1997-03-19 | — | — | EP | disclosed |
| EP-0601668-A2 | Epoxy resin composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-06-15 | — | — | EP | disclosed |