Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 3/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.57 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.55 |
| ▸ | TFPI | P10646 | 1/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.54 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.53 |
| ▸ | CALCR | P30988 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780556 | 1.00 | NTSR1 (0.59) | NTSR1OPRD1NTSR2EPHA2KEAP1 | |
| SCHEMBL8780541 | 0.93 | OPRD1 (0.58) | NTSR1OPRD1NTSR2EPHA2TFPI | |
| SCHEMBL31519869 | 0.87 | OPRD1 (0.64) | NTSR1OPRD1NTSR2 | |
| SCHEMBL30137653 | 0.86 | TFPI (0.69) | EPHA2TFPINMUR2NMUR1 | |
| SCHEMBL31511426 | 0.86 | MAPK8 (0.57) | NTSR1OPRD1NTSR2EPHA2KEAP1 | |
| SCHEMBL30312779 | 0.86 | NTSR1 (0.72) | NTSR1NTSR2NPY1R | |
| SCHEMBL29553166 | 0.85 | NPY2R (0.59) | NTSR1TFPINMUR2NMUR1NPY1R | |
| SCHEMBL9807257 | 0.85 | NTSR1 (0.62) | NTSR1NTSR2EPHA2NPY1R | |
| SCHEMBL30186407 | 0.84 | EPHA2 (0.58) | EPHA2TFPINMUR2NMUR1NPY1R | |
| SCHEMBL30302482 | 0.84 | NMUR2 (0.62) | OPRD1EPHA2TFPINMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667786-A4 | RETRO-, INVERSO-, AND RETRO-INVERSO SYNTHETIC PEPTIDE ANALOGUES. | DEAKIN RES LTD (AU) | 1997-08-06 | — | — | EP | disclosed |
| EP-0667786-A1 | RETRO-, INVERSO-, AND RETRO-INVERSO SYNTHETIC PEPTIDE ANALOGUES | DEAKIN RESEARCH LIMITED (AU) | 1995-08-23 | — | — | EP | disclosed |