SCHEMBL29553166

SCHEMBL29553166

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)CN)C(C)C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 7/20 0.59
▸ NPY4R P50391 7/20 0.59
▸ NPY5R Q15761 7/20 0.59
▸ NPY1R P25929 5/20 0.59
▸ EP300 Q09472 1/20 0.58
▸ HIF1A Q16665 1/20 0.58
▸ NTSR1 P30989 1/20 0.57
▸ TFPI P10646 3/20 0.56
▸ NMUR2 Q9GZQ4 3/20 0.55
▸ NMUR1 Q9HB89 3/20 0.55
▸ KDM1A O60341 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29551993 0.91 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29360416 0.90 NPY2R (0.66) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30199009 0.86 MAPK8 (0.59) NTSR1
SCHEMBL31012331 0.86 MAPK8 (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30335722 0.86 TFPI (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30906476 0.85 NPY2R (0.71) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31670651 0.85 NTSR1 (0.56) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL8780544 0.85 NTSR1 (0.59) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL8780556 0.85 NTSR1 (0.59) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL29359777 0.85 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565665-B2 Compositions and methods for controlled mRNA translation and stability TRUSTEES OF BOSTON UNIVERSITY (US) 2026-03-03 — — US disclosed
US-20250243247-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION TRUSTEES OF BOSTON UNIVERSITY (US) 2025-07-31 — — US disclosed
US-12202863-B2 Chimeric antigen receptor (CAR) modulation TRUSTEES OF BOSTON UNIVERSITY (US) 2025-01-21 — — US disclosed
US-12180485-B2 Repressible control of gene expression TRUSTEES OF BOSTON UNIVERSITY (US) 2024-12-31 — — US disclosed
US-20240263193-A1 COMPOSITIONS AND METHODS FOR CONTROLLED MRNA TRANSLATION AND STABILITY TRUSTEES OF BOSTON UNIVERSITY (US) 2024-08-08 — — US disclosed
US-20230279406-A1 INDUCIBLE CONTROL OF GENE EXPRESSION TRUSTEES OF BOSTON UNIVERSITY (US) 2023-09-07 — — US disclosed
US-11572565-B2 Inducible control of gene expression TRUSTEES OF BOSTON UNIVERSITY (US) 2023-02-07 — — US disclosed
US-20220098246-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION TRUSTEES OF BOSTON UNIVERSITY (US) 2022-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565665-B2 Compositions and methods for controlled mRNA translation and stability ADAR, ADA, NSUN2 NPY2R 4475/4885NPY4R 4647/4885NPY5R 4832/4885
US-20250243247-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION HAVCR2, CPB1, CTRL NPY2R 3151/4885NPY4R 3416/4885NPY5R 3573/4885
US-20220098246-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION HAVCR2, CPB1, CTRL NPY2R 3151/4885NPY4R 3416/4885NPY5R 3573/4885
US-12202863-B2 Chimeric antigen receptor (CAR) modulation HAVCR2, CPB1, CTRL NPY2R 3151/4885NPY4R 3416/4885NPY5R 3573/4885
US-20240263193-A1 COMPOSITIONS AND METHODS FOR CONTROLLED MRNA TRANSLATION AND STABILITY ADAR, ADA, RNGTT NPY2R 4866/4885NPY4R 4880/4885NPY5R 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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