SCHEMBL9807257

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	NTSR1	P30989	14/20	0.62

▸	NTSR2	O95665	11/20	0.62

▸	NPY1R	P25929	1/20	0.62

▸	SORT1	Q99523	10/20	0.59

▸	EPHA2	P29317	2/20	0.59

▸	AGTR1	P30556	1/20	0.57

▸	AGTR2	P50052	1/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9807269	0.94	EPHA2 (0.63)	NTSR1NTSR2NPY1RSORT1EPHA2
SCHEMBL9807253	0.91	EPHA2 (0.58)	NTSR1NTSR2NPY1REPHA2
SCHEMBL9807235	0.91	EPHA2 (0.64)	NPY1REPHA2
SCHEMBL9807252	0.91	EPHA2 (0.62)	EPHA2
SCHEMBL9807306	0.91	EPHA2 (0.62)	EPHA2
SCHEMBL9691456	0.89	EPHA2 (0.61)	EPHA2AGTR1AGTR2
SCHEMBL9807262	0.88	EPHA2 (0.61)	NTSR1NTSR2NPY1REPHA2
SCHEMBL8700587	0.88	NTSR1 (0.63)	NTSR1NTSR2NPY1RSORT1
SCHEMBL9807265	0.87	EPHA2 (0.61)	NTSR1NTSR2NPY1RSORT1EPHA2
SCHEMBL30034783	0.87	NTSR2 (0.73)	NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0146266-B1	ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES	ORTHO PHARMACEUTICAL CORPORATION (US)	1991-05-22	—	—	EP	disclosed
EP-0146266-A2	Enzyme-resistant immunomodulatory peptides	ORTHO PHARMACEUTICAL CORPORATION (US)	1985-06-26	—	—	EP	disclosed