Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 8/20 | 0.77 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.74 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.74 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.72 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.72 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.72 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.72 |
| ▸ | LDHA | P00338 | 1/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.72 |
| ▸ | FBP1 | P09467 | 1/20 | 0.72 |
| ▸ | SRC | P12931 | 1/20 | 0.72 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.72 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.72 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.72 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780682 | 1.00 | DNPH1 (0.77) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL31029196 | 0.92 | P2RX3 (0.86) | DNPH1P2RX3P2RX2TRPM2SRC | |
| SCHEMBL26067680 | 0.91 | DNPH1 (0.75) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL4307198 | 0.91 | DNPH1 (0.75) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL30004415 | 0.91 | DNPH1 (0.75) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL17878170 | 0.91 | DNPH1 (0.72) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL17881927 | 0.91 | DNPH1 (0.72) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL20705930 | 0.91 | DNPH1 (0.72) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL17868387 | 0.91 | DNPH1 (0.72) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL14358309 | 0.90 | DNPH1 (0.74) | DNPH1TAS1R3TAS1R1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |