Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.36 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797782 | 0.86 | GRM5 (0.41) | NPC1ALDH1A1CHRM3 | |
| SCHEMBL7803049 | 0.72 | CES2 (0.41) | MAPTALDH1A1RAB9AKMT2APOLB | |
| SCHEMBL6945739 | 0.69 | CES2 (0.42) | ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7797786 | 0.67 | GRM5 (0.43) | NPC1RAB9ACHRM3POLB | |
| SCHEMBL18936242 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL28799843 | 0.66 | LMNA (0.54) | NPC1MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18936355 | 0.64 | NPC1 (0.48) | NPC1ALDH1A1RAB9AL3MBTL1PTPN1 | |
| SCHEMBL7803902 | 0.63 | GRM5 (0.42) | NPC1ALDH1A1RAB9AKMT2ACHRM3 | |
| SCHEMBL361933 | 0.63 | CES1 (0.60) | NPC1MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29668746 | 0.63 | CES1 (0.60) | NPC1MAPTALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814079-A1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-12-29 | — | — | EP | disclosed |