Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780885 | 0.88 | HPGD (0.39) | BRPF1LMNADRD2DRD3RXFP1 | |
| SCHEMBL8780929 | 0.88 | KCNH2 (0.42) | LMNAHTR2ADRD3 | |
| SCHEMBL8780747 | 0.84 | KDM4E (0.42) | HTR6LMNADRD2HTR2AHTR2C | |
| SCHEMBL8780864 | 0.84 | KCNH2 (0.44) | LMNAHTR2ADRD3 | |
| Fumaric Acid SCHEMBL8780803 | 0.83 | KCNH2 (0.39) | HTR2ADRD3RXFP1 | |
| Fumaric Acid SCHEMBL8780807 | 0.83 | KCNH2 (0.39) | HTR2ADRD3RXFP1 | |
| SCHEMBL8780834 | 0.79 | KMT2A (0.39) | HTR6BRD4DRD2HTR2AHTR2C | |
| SCHEMBL8780889 | 0.79 | SLC22A2 (0.40) | DRD2DRD3MAPTCYP3A4CYP2D6 | |
| SCHEMBL8780780 | 0.77 | KCNH2 (0.42) | BRPF1LMNAHTR2ADRD3RXFP1 | |
| SCHEMBL8780863 | 0.77 | KCNH2 (0.41) | LMNAHTR2ADRD3RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |