Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780985 | 0.70 | GPR84 (0.42) | ALDH1A1NPSR1 | |
| SCHEMBL11488686 | 0.69 | CYP3A4 (0.35) | ALDH1A1MAPTCYP3A4CYP2B6 | |
| SCHEMBL8781046 | 0.68 | POLB (0.36) | ALDH1A1MAPT | |
| SCHEMBL26815268 | 0.65 | ATM (0.35) | ALDH1A1 | |
| SCHEMBL25061759 | 0.63 | ADORA2B (0.38) | ALDH1A1MAPTCASP3NPSR1SENP8 | |
| SCHEMBL17841299 | 0.61 | TYMP (0.35) | ALDH1A1MAPT | |
| SCHEMBL1318483 | 0.61 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL5551663 | 0.59 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL11731417 | 0.58 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2B6 | |
| SCHEMBL24759399 | 0.58 | ADORA2B (0.37) | ALDH1A1MAPTNPSR1CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |