Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633238 | 0.96 | BCHE (0.51) | BCHEACHEALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL5866144 | 0.92 | BCHE (0.55) | BCHEACHEALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL18934371 | 0.89 | ALDH1A1 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL2567795 | 0.89 | ALDH1A1 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL1619467 | 0.85 | ALDH1A1 (0.53) | BCHEACHEALDH1A1CYP2A6TSHR | |
| SCHEMBL18926560 | 0.84 | GAA (0.50) | BCHEACHEALDH1A1CA12CA1 | |
| SCHEMBL4502821 | 0.83 | HCRTR2 (0.43) | BCHEACHEALDH1A1CYP19A1TSHR | |
| SCHEMBL1979822 | 0.83 | BCHE (0.57) | BCHEACHEALDH1A1CYP2A6CYP19A1 | |
| SCHEMBL18926554 | 0.83 | CA2 (0.53) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL4793354 | 0.82 | FKBP1A (0.52) | BCHEACHEALDH1A1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |