Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15487036 | 0.87 | ALDH1A1 (0.39) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL31678993 | 0.83 | ALDH1A1 (0.41) | BTN3A1ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL877722 | 0.80 | TDP1 (0.41) | BTN3A1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL722000 | 0.77 | KMT2A (0.40) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL1028181 | 0.76 | BTN3A1 (0.40) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL12452547 | 0.74 | ALDH1A1 (0.43) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL547016 | 0.74 | L3MBTL1 (0.50) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL1786794 | 0.74 | ALDH1A1 (0.40) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL1786739 | 0.74 | BTN3A1 (0.41) | BTN3A1ALDH1A1HSD17B10PGRGAA | |
| SCHEMBL7807907 | 0.74 | KMT2A (0.40) | BTN3A1ALDH1A1HSD17B10MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040126-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-29 | — | — | WO | disclosed |