SCHEMBL547016

SCHEMBL547016

O=P(O)(Oc1cccc2ccccc12)Oc1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
KMT2A Q03164 2/20 0.50
GPR84 Q9NQS5 1/20 0.50
HTT P42858 1/20 0.50
MEN1 O00255 1/20 0.50
RAB9A P51151 1/20 0.50
BTN3A1 O00481 2/20 0.49
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 2/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
OGG1 O15527 1/20 0.47
HSD17B10 Q99714 3/20 0.47
PGR P06401 1/20 0.47
GAA P10253 1/20 0.47
PTGS1 P23219 1/20 0.47
MAPK1 P28482 1/20 0.47
ACP3 P15309 1/20 0.47
PTK2B Q14289 1/20 0.46
INPPL1 O15357 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28178041 0.98 HTT (0.49) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL29175021 0.98 HTT (0.49) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL14841055 0.94 HTT (0.47) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL27538515 0.91 GPR84 (0.51) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL3717591 0.91 HTT (0.50) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL29206847 0.90 HTT (0.47) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL5251402 0.90 HTT (0.47) L3MBTL1KMT2AGPR84HTTMEN1
Propene SCHEMBL27755920 0.90 BTN3A1 (0.49) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL25229090 0.89 HTT (0.49) L3MBTL1KMT2AGPR84HTTMEN1
SCHEMBL25259138 0.89 HTT (0.46) L3MBTL1KMT2AGPR84HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136918-A Method for preparing 4- (2, 2-diaryl vinyl) thiophosphorus/phosphonate 岳阳凯茂化工材料有限公司 2025-06-13 CN claimed
CN-118878452-B Isoindolinone derived unsaturated imine compound, synthesis method thereof and application thereof in anti-tumor activity 徐州市第一人民医院 2025-01-24 CN claimed
CN-118955508-A Alpha-indolylpyrrolo [1,2-a ] indole derivative and preparation method thereof 浙江大学 2024-11-15 CN claimed
CN-118878452-A Isoindolinone derived unsaturated imine compound, synthesis method thereof and application thereof in anti-tumor activity 徐州市第一人民医院 2024-11-01 CN claimed
CN-113109406-B Method for constructing electrochemiluminescence aptamer sensor for omethoate detection 江苏大学 2023-04-07 CN claimed
CN-115677451-A Method for preparing trans-dibenzyl ethylene compound 中国科学院大连化学物理研究所 2023-02-03 CN claimed
CN-113173925-B Benzoxoepinoindole derivative and preparation method thereof 浙江大学 2022-11-11 CN claimed
US-11440871-B2 Zuclomiphene salts and crystalline forms thereof APOTEX INC. (CA) 2022-09-13 US claimed
CN-113993855-A Method for synthesizing 5-hydroxymethylfurfural IFP 新能源公司 2022-01-28 CN claimed
CN-110590835-B Method for preparing 2-iodo-1-phosphoryl substituted alkane compound by high-efficiency double functionalization of olefin 湖南理工学院 2021-09-07 CN claimed
EP-2017271-A1 Process for the preparation of escitalopram Aurobindo Pharma Limited (IN) 2009-01-21 EP claimed
US-20090018351-A1 PREPARATION OF ESCITALOPRAM DR. REDDY'S LABORATORIES, INC. (US) 2009-01-15 US claimed
EP-1706394-A4 PREPARATION OF ESCITALOPRAM REDDYS LAB INC DR (US) 2008-10-22 EP claimed
EP-1877394-A1 PROCESS FOR THE PREPARATION OF ESCITALOPRAM OR ITS ACID ADDITION SALTS Jubilant Organosys Limited (IN) 2008-01-16 EP claimed
WO-2006106531-A1 PROCESS FOR THE PREPARATION OF ESCITALOPRAM OR ITS ACID ADDITION SALTS JUBILANT ORGANOSYS LTD (IN) 2006-10-12 WO claimed
EP-1706394-A1 PREPARATION OF ESCITALOPRAM Dr. Reddy's Laboratories, Inc. (US) 2006-10-04 EP claimed
US-20050154051-A1 Method for the preparation of escitalopram H. LUNDBECK A/S (DK) 2005-07-14 US claimed
WO-2005047274-A1 PREPARATION OF ESCITALOPRAM DR. REDDY'S LABORATORIES, INC. (US) 2005-05-26 WO claimed
EP-1458701-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. Lundbeck A/S (DK) 2004-09-22 EP claimed
WO-2003051861-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. LUNDBECK A/S (DK) 2003-06-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440871-B2 Zuclomiphene salts and crystalline forms thereof ZP1, ZYX, ALPP L3MBTL1 915/4885KMT2A 1497/4885GPR84 2229/4885
US-20050154051-A1 Method for the preparation of escitalopram SLC6A4, TPH2, SLC6A3 L3MBTL1 4350/4885KMT2A 1280/4885GPR84 3802/4885
US-20090018351-A1 PREPARATION OF ESCITALOPRAM HTR4, SLC6A4, HTR5A L3MBTL1 3278/4885KMT2A 630/4885GPR84 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.