Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458660 | 0.76 | CYP1A2 (0.45) | KDM4EALDH1A1RXRARXRBRXRG | |
| SCHEMBL8784327 | 0.74 | NR1H2 (0.43) | KDM4EEGLN1KMT2APPARGPPARA | |
| SCHEMBL15021728 | 0.73 | EGLN1 (0.44) | RXRARXRBRXRGEGLN1PPARG | |
| SCHEMBL8785285 | 0.71 | MAPT (0.40) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16673286 | 0.67 | L3MBTL1 (0.46) | KDM4EALDH1A1GAATDP1KMT2A | |
| SCHEMBL446924 | 0.67 | RXRA (0.53) | KDM4EALDH1A1RXRARXRBRXRG | |
| SCHEMBL27467077 | 0.66 | KCNN4 (0.46) | ALDH1A1GAA | |
| SCHEMBL15709753 | 0.65 | HTR7 (0.44) | KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9373829 | 0.64 | ALOX5 (0.41) | KDM4EEGLN1 | |
| Nafcaproic Acid SCHEMBL2109457 | 0.64 | ACP3 (0.45) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623122-B1 | Benzopyran and related LTB4-antagonists. | PFIZER (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5550152-A | ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-08-27 | — | — | US | disclosed |