Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18980126 | 0.82 | MEN1 (0.61) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL23121958 | 0.82 | TSHR (0.39) | PTGS1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL19286604 | 0.81 | TSHR (0.53) | PTGS1RECQLHSD17B10ALDH1A1HTT | |
| SCHEMBL1691731 | 0.81 | PTGS1 (0.52) | PTGS1MEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL8783376 | 0.81 | PTGS1 (0.56) | PTGS1MEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL17582636 | 0.80 | PTGS1 (0.54) | PTGS1MEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL26915733 | 0.80 | NPBWR1 (0.60) | NPBWR1MAPTPKM | |
| SCHEMBL20443987 | 0.78 | PTGS1 (0.49) | PTGS1RECQLHSD17B10ALDH1A1HTT | |
| SCHEMBL19746474 | 0.78 | PTGS1 (0.49) | PTGS1MEN1KMT2ARECQLHSD17B10 | |
| SCHEMBL17595809 | 0.78 | PTGS1 (0.52) | PTGS1MEN1KMT2ARECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040829-C | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1998-11-25 | — | — | CN | disclosed |
| EP-0398293-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5278163-A | Insecticides, pesticides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| EP-0398293-A1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |