Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307463 | 0.85 | KDM4E (0.53) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8786172 | 0.85 | ALDH1A1 (0.57) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL7115026 | 0.84 | MAPT (0.59) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8785838 | 0.83 | CA1 (0.56) | KDM4EALDH1A1KMT2AL3MBTL1CA1 | |
| SCHEMBL9306855 | 0.83 | KDM4E (0.51) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8201626 | 0.81 | L3MBTL1 (0.60) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL11330155 | 0.81 | KDM4E (0.56) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8784891 | 0.80 | PIM1 (0.59) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL11480049 | 0.80 | MAOB (0.71) | KDM4EMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL14307644 | 0.80 | ERAP1 (0.61) | KDM4EMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| CN-1090274-A | Condensed heterocyclic compounds and its preparation method and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-08-03 | — | — | CN | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |